Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100009 | 0.80 | HSD17B1 (0.58) | HSD17B1HSD17B2ESR2ESR1 | |
| SCHEMBL12668310 | 0.77 | HSD17B1 (0.60) | HSD17B1HSD17B2ESR2ESR1HSD17B14 | |
| SCHEMBL675046 | 0.77 | HSD17B1 (0.63) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL31574448 | 0.77 | HSD17B1 (0.63) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL29696046 | 0.77 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL12325403 | 0.77 | PDGFRB (0.52) | TDP1ERN1 | |
| SCHEMBL29429121 | 0.77 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL272034 | 0.77 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL26979937 | 0.77 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2ESR1FGFR1 | |
| SCHEMBL20056528 | 0.77 | ABL1 (0.60) | HSD17B1HSD17B2ESR2TLR8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |