Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23030247 | 0.78 | KISS1R (0.33) | KISS1RPAOXEPHX1 | |
| SCHEMBL19935801 | 0.70 | EPHX1 (0.41) | KISS1RPAOXHTR2AHRH1EPHX1 | |
| SCHEMBL19566124 | 0.70 | KISS1R (0.36) | KISS1RPAOXHTR2AHRH1EPHX1 | |
| SCHEMBL24741439 | 0.69 | KISS1R (0.33) | KISS1REPHX1 | |
| SCHEMBL24098189 | 0.68 | HTR2A (0.34) | KISS1RPAOXHTR2AHRH1EPHX1 | |
| SCHEMBL172994 | 0.68 | — | — | |
| SCHEMBL16221904 | 0.67 | — | — | |
| SCHEMBL21346194 | 0.67 | — | — | |
| SCHEMBL23621946 | 0.67 | EPHX1 (0.42) | PAOXHTR2AHRH1EPHX1 | |
| SCHEMBL22867561 | 0.65 | KISS1R (0.44) | KISS1RHTR2AHRH1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |