Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20805862 | 0.86 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL12997526 | 0.86 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL16978942 | 0.86 | HSD17B10 (0.48) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL135177 | 0.84 | L3MBTL1 (0.58) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL133363 | 0.84 | L3MBTL1 (0.58) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL47049 | 0.84 | L3MBTL1 (0.58) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL1467517 | 0.84 | HSD17B10 (0.49) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL3576321 | 0.84 | HSD17B10 (0.49) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL6899788 | 0.84 | HSD17B10 (0.49) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL3141725 | 0.84 | HSD17B10 (0.49) | HSD17B10ALDH1A1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883627-B1 | BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2018-04-18 | — | — | EP | disclosed |