SCHEMBL135177

SCHEMBL135177

CC(C)(C)OC(=O)N1CCC[C@@H]1CO

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
POLB P06746 1/20 0.58
HSD17B10 Q99714 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.44
NPC1 O15118 1/20 0.43
PDE8B O95263 1/20 0.43
ATM Q13315 2/20 0.43
NR1H2 P55055 1/20 0.43
OPRD1 P41143 1/20 0.43
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47049 1.00 L3MBTL1 (0.58) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL133363 1.00 L3MBTL1 (0.58) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
Methylene Chloride SCHEMBL28081516 0.95 POLB (0.53) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL282976 0.95 POLB (0.51) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL282977 0.95 POLB (0.51) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL192841 0.95 POLB (0.51) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL31323435 0.94 POLB (0.50) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL31048468 0.94 POLB (0.50) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL20399730 0.94 POLB (0.50) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1
SCHEMBL3769601 0.93 HPGD (0.54) L3MBTL1POLBHSD17B10SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493628-A Quantum dot ink and preparation method of quantum dot film TCL科技集团股份有限公司 2021-10-12 CN claimed
CN-113122053-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
JP-3052857-A None JP disclosed
EP-3710458-B1 IMMUNOPROTEASOME INHIBITORS PRINCIPIA BIOPHARMA INC (US) 2026-03-25 EP disclosed
EP-4714446-A2 PHARMACEUTICAL COMPOUNDS Nxera Pharma UK Limited (GB) 2026-03-25 EP disclosed
US-20260078121-A1 INHIBITORS OF ENL/AF9 YEATS AND FLT3 BRIDGE MEDICINES (US) 2026-03-19 US disclosed
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20260049054-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SANIONA AS (DK) 2026-02-19 US disclosed
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 EP disclosed
US-20260035365-A1 1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF MUTANT EGFR FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2026-02-05 US disclosed
EP-4317162-B1 1,3-BENZODIOXOLANE-CONTAINING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF XIAN XINTONG PHARMACEUTICAL RES CO LTD (CN) 2026-02-04 EP disclosed
WO-1994008992-A1 HETEROCYCLIC ETHER COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION ABBOTT LABORATORIES (US) 1994-04-28 WO disclosed
WO-1994002477-A1 IMIDAZOLE, TRIAZOLE AND TETRAZOLE DERIVATIVES MERCK SHARP & DOHME LIMITED (GB) 1994-02-03 WO disclosed
US-5242914-A 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics SANKYO COMPANY, LIMITED (JP) 1993-09-07 US disclosed
US-5021436-A Antiulcer, anticoagulant, antiischaemic agent BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) 1991-06-04 US disclosed
US-4999362-A Hypotensive, Antiulcer, Cytoprotective, Antithrombotic Agents BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1991-03-12 US disclosed
JP-H0352857-A 1-SUBSTITUTED-2-(3-AMINO-1-PROPYNYL)PYRROLIDINE DERIVATIVE AMERICAN CYANAMID CO 1991-03-07 JP disclosed
US-4902684-A Benzazepine and benzothiazepine derivatives E. R. SQUIBB & SONS, INC. (US) 1990-02-20 US disclosed
WO-1989012633-A1 BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES E.R. SQUIBB & SONS, INC. (US) 1989-12-28 WO disclosed
EP-0337637-A1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics Sankyo Company Limited (JP) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559462-B2 Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto HTR2C, HTR1A, HTR2A L3MBTL1 3206/4885POLB 3873/4885HSD17B10 960/4885
US-20260049054-A1 NOVEL POTASSIUM CHANNEL INHIBITORS SCN10A, KCNK10, KCNJ2 L3MBTL1 4136/4885POLB 4820/4885HSD17B10 1259/4885
US-20260078121-A1 INHIBITORS OF ENL/AF9 YEATS AND FLT3 MLLT3, MLLT1, FLT3 L3MBTL1 170/4885POLB 4206/4885HSD17B10 2268/4885
US-20260035365-A1 1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF MUTANT EGFR FOR THE TREATMENT OF CANCER EGFR, ERBB2, ERBB3 L3MBTL1 513/4885POLB 781/4885HSD17B10 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.