Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057136 | 1.00 | VSIR (0.43) | VSIRCD274TGFBR1MAPTALDH1A1 | |
| SCHEMBL24058535 | 1.00 | VSIR (0.43) | VSIRCD274TGFBR1MAPTALDH1A1 | |
| SCHEMBL20057150 | 0.92 | VSIR (0.36) | VSIRCD274TGFBR1MAPTALDH1A1 | |
| SCHEMBL24595269 | 0.92 | VSIR (0.41) | VSIRCD274MAPTALDH1A1LMNA | |
| SCHEMBL24058479 | 0.89 | VSIR (0.43) | VSIRCD274MAPTCA2CA1 | |
| SCHEMBL19969099 | 0.89 | VSIR (0.39) | VSIRCD274TGFBR1MAPTCA2 | |
| SCHEMBL24058650 | 0.88 | FOLH1 (0.43) | VSIRCD274 | |
| SCHEMBL24058460 | 0.88 | FOLH1 (0.38) | VSIRCD274MAPTCA2CA1 | |
| SCHEMBL24058693 | 0.88 | FOLH1 (0.43) | VSIRCD274 | |
| SCHEMBL24595229 | 0.88 | FOLH1 (0.38) | VSIRCD274MAPTCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041827-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-04-18 | — | — | EP | disclosed |