Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 7/20 | 0.37 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057096 | 0.88 | VSIR (0.45) | ZAP70BMP1VSIRCD274 | |
| SCHEMBL20057341 | 0.88 | VSIR (0.45) | ZAP70BMP1VSIRCD274 | |
| SCHEMBL19969263 | 0.81 | VSIR (0.47) | SRCZAP70VSIRCD274 | |
| SCHEMBL19969098 | 0.81 | VSIR (0.47) | SRCZAP70VSIRCD274 | |
| SCHEMBL19969055 | 0.81 | VSIR (0.47) | SRCZAP70VSIRCD274 | |
| SCHEMBL24086186 | 0.81 | VSIR (0.47) | SRCZAP70VSIRCD274 | |
| SCHEMBL21738382 | 0.80 | CD274 (0.58) | SRCZAP70BMP1VSIRCD274 | |
| SCHEMBL21168248 | 0.77 | VSIR (0.39) | SRCBMP1VSIRCD274 | |
| SCHEMBL24668840 | 0.76 | VSIR (0.39) | VSIRCD274 | |
| SCHEMBL21168278 | 0.74 | VSIR (0.38) | SRCBMP1VSIRCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363790-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| EP-3041827-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-04-18 | — | — | EP | disclosed |