Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 2/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20057341 | 1.00 | VSIR (0.45) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL20057098 | 0.88 | SRC (0.39) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL21738738 | 0.83 | VSIR (0.43) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL20057106 | 0.82 | VSIR (0.67) | VSIRCD274BMP1 | |
| SCHEMBL21738417 | 0.82 | VSIR (0.67) | VSIRCD274BMP1 | |
| SCHEMBL20057381 | 0.80 | VSIR (0.56) | VSIRCD274BMP1 | |
| SCHEMBL20057110 | 0.79 | VSIR (0.43) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL20057130 | 0.79 | CD274 (0.72) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL20057132 | 0.79 | CD274 (0.72) | VSIRCD274BMP1ZAP70 | |
| SCHEMBL20170530 | 0.78 | VSIR (0.34) | VSIRCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363790-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018073754-A1 | DUAL INHIBITORS OF VISTA AND PD-1 PATHWAYS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-04-26 | — | — | WO | disclosed |
| EP-3041827-B1 | 1,2,4-OXADIAZOLE DERIVATIVES AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-04-18 | — | — | EP | disclosed |