Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14240668 | 0.75 | CNR2 (0.38) | CNR2CNR1BACE1 | |
| SCHEMBL19779403 | 0.72 | VNN1 (0.37) | — | |
| SCHEMBL12133618 | 0.69 | CNR2 (0.39) | CNR2CNR1BACE1 | |
| SCHEMBL2053631 | 0.65 | OPRL1 (0.44) | CNR2BACE1 | |
| SCHEMBL15998512 | 0.65 | OPRL1 (0.36) | CNR2CNR1BACE1 | |
| SCHEMBL2640915 | 0.65 | ALDH1A1 (0.38) | CNR2BACE1 | |
| SCHEMBL1356476 | 0.64 | CNR2 (0.40) | CNR2 | |
| Hydrochloric Acid SCHEMBL14152305 | 0.64 | ALDH1A1 (0.37) | CNR2BACE1 | |
| SCHEMBL19225509 | 0.63 | CNR1 (0.31) | CNR2CNR1 | |
| SCHEMBL12258763 | 0.63 | OPRL1 (0.36) | CNR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3072886-B1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-04-18 | — | — | EP | disclosed |