⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008166 | 0.81 | — | — | |
| SCHEMBL2006075 | 0.79 | DNM1 (0.41) | — | |
| SCHEMBL1107764 | 0.78 | — | — | |
| SCHEMBL2007000 | 0.77 | DNM1 (0.46) | — | |
| SCHEMBL2003715 | 0.77 | DNM1 (0.46) | — | |
| SCHEMBL1889268 | 0.74 | — | — | |
| SCHEMBL9814681 | 0.73 | — | — | |
| SCHEMBL3672238 | 0.73 | DNM1 (0.41) | — | |
| SCHEMBL4849944 | 0.72 | — | — | |
| SCHEMBL12361970 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964738-B2 | Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives | SILAMED, INC. (US) | 2011-06-21 | — | — | US | claimed |
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | claimed |
| EP-1737471-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND Pharmaceuticals (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005102358-A2 | SILICONE-SUBSTITUTED COX-2 SELECTIVE INHIBITORS | RND PHARMACEUTICALS (US) | 2005-11-03 | — | — | WO | claimed |
| CN-117700994-B | Graphene modified polyimide film and preparation method thereof | 苏州聚萃材料科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117700994-A | Graphene modified polyimide film and preparation method thereof | 苏州聚萃材料科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20240026102-A1 | RECYCLING OF FIBER REINFORCED THERMOSET AND THERMOPLASTIC COMPOSITES AND PREPEGS USING SOLVENTS AND CATALYSTS | WEST VIRGINIA UNIVERSITY | 2024-01-25 | — | — | US | disclosed |
| WO-2022061358-A1 | RECYCLING OF FIBER REINFORCED THERMOSET AND THERMOPLASTIC COMPOSITES AND PREPEGS USING SOLVENTS AND CATALYSTS | West Virginia University Board of Governors on behalf of West Virginia University (US) | 2022-03-24 | — | — | WO | disclosed |
| US-7964738-B2 | Pharmaceutical compositions and methods of use of lipophilic, silicon-substituted, cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs and derivatives | SILAMED, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090306015-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | SILAMED, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | L'OREAL (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20090054369-A1 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND PHARMACEUTICALS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2007073560-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF HIGHLY LIPOPHILIC SULFHYDRYL COMPOUNDS | RND PHARMACEUTICALS, INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | disclosed |
| CN-1304340-C | Process for preparing amine propyl functional porous material | SHANXI COAL CHEM INST (CN) | 2007-03-14 | — | — | CN | disclosed |
| WO-2007019221-A2 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| EP-1737471-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND Pharmaceuticals (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005102358-A2 | SILICONE-SUBSTITUTED COX-2 SELECTIVE INHIBITORS | RND PHARMACEUTICALS (US) | 2005-11-03 | — | — | WO | disclosed |
| CN-1603832-A | Pathogenic bacteria immune detection chip and preparation method thereof | UNIV SOUTHEAST (CN) | 2005-04-06 | — | — | CN | disclosed |
| US-20050008588-A1 | Aminoarylvinyl-s-triazine compounds and uses thereof | L'OREAL (FR) | 2005-01-13 | — | — | US | disclosed |