Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060020 | 0.87 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060005 | 0.79 | — | — | |
| SCHEMBL20060139 | 0.79 | CMA1 (0.39) | ALDH1A1 | |
| SCHEMBL20060018 | 0.78 | — | — | |
| SCHEMBL20060140 | 0.75 | — | — | |
| SCHEMBL20059913 | 0.74 | — | — | |
| SCHEMBL20060002 | 0.71 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL20060159 | 0.70 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060161 | 0.70 | — | — | |
| SCHEMBL20060184 | 0.70 | MEN1 (0.30) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |