Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060163 | 0.86 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060189 | 0.82 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20059919 | 0.80 | MEN1 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL24166301 | 0.77 | — | — | |
| SCHEMBL20059913 | 0.77 | — | — | |
| SCHEMBL20059969 | 0.76 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060195 | 0.74 | MEN1 (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060143 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL20060020 | 0.72 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20060161 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |