Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060207 | 0.89 | KMT2A (0.35) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL20060035 | 0.80 | KDM4E (0.36) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20059942 | 0.79 | — | — | |
| SCHEMBL20060031 | 0.78 | — | — | |
| SCHEMBL20060156 | 0.73 | — | — | |
| SCHEMBL20060200 | 0.71 | KMT2A (0.45) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20060215 | 0.71 | — | — | |
| SCHEMBL20059926 | 0.71 | — | — | |
| SCHEMBL20060129 | 0.70 | — | — | |
| SCHEMBL20060027 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |