Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060210 | 0.80 | — | — | |
| SCHEMBL20060197 | 0.78 | — | — | |
| SCHEMBL20060185 | 0.77 | — | — | |
| SCHEMBL20060150 | 0.76 | KDM4E (0.31) | KMT2AKDM4EMEN1 | |
| SCHEMBL20060207 | 0.72 | KMT2A (0.35) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20060208 | 0.71 | KDM4E (0.34) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20060035 | 0.67 | KDM4E (0.36) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20060212 | 0.66 | MAPT (0.32) | KMT2AALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11665421 | 0.65 | ADH1B (0.50) | KMT2AALDH1A1SMN1; SMN2L3MBTL1ADH1B | |
| SCHEMBL1309772 | 0.63 | KMT2A (0.94) | KMT2AALDH1A1SMN1; SMN2L3MBTL1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |