Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.49 |
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | BMP4 | P12644 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524662 | 0.84 | ACVR1 (0.50) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL27737402 | 0.81 | CA12 (0.63) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL12386951 | 0.81 | CA12 (0.59) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL23555710 | 0.80 | CA12 (0.61) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL12074247 | 0.80 | CA12 (0.65) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL4658401 | 0.79 | CA12 (0.59) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL4073648 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL8011323 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL6296099 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9ACVR1 | |
| SCHEMBL20371605 | 0.78 | KDM4E (0.47) | CA12CA1CA2CA9ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111940-A1 | IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180111940-A1 | IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-26 | — | — | US | disclosed |
| US-20180108845-A1 | CYCLIC UREA COMPOUNDS FOR ELECTRONIC DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-19 | — | — | US | disclosed |
| US-20180108845-A1 | CYCLIC UREA COMPOUNDS FOR ELECTRONIC DEVICES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111940-A1 | IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES | KCNJ2, KCNJ5, IKZF1 | CA12 3266/4885CA1 4130/4885CA2 3275/4885 |
| US-20180108845-A1 | CYCLIC UREA COMPOUNDS FOR ELECTRONIC DEVICES | SLC14A1, ODC1, UROD | CA12 3070/4885CA1 2666/4885CA2 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.