SCHEMBL20061669

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6611829	0.87	PDE2A (0.47)	PDE2AEPHX2CACNA1HHCRTR1HCRTR2
	SCHEMBL20061666	0.84	PDE2A (0.42)	PDE2AEPHX2ALOX15CACNA1HHCRTR1
	SCHEMBL20128505	0.83	ALOX15 (0.43)	ALOX15ALOX12FOSTTRJUN
	SCHEMBL18181376	0.83	PDE2A (0.43)	PDE2AEPHX2CACNA1HHCRTR1HCRTR2
	SCHEMBL20061670	0.82	ALOX15 (0.60)	ALOX15ALOX12FOSTTRJUN
	SCHEMBL20132766	0.81	ALOX5AP (0.36)	PDE2AEPHX2ALOX15CACNA1HHCRTR1
	SCHEMBL6600311	0.81	TP53 (0.45)	PDE2AEPHX2CACNA1HTP53HCRTR1
	SCHEMBL18174275	0.80	EPHX2 (0.50)	PDE2AEPHX2CACNA1HPPARG
	SCHEMBL20128512	0.80	EPHX2 (0.50)	PDE2AEPHX2CACNA1H
	SCHEMBL18174185	0.80	EPHX2 (0.50)	PDE2AEPHX2CACNA1HPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.