Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | PDE2A | O00408 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611829 | 0.83 | PDE2A (0.47) | EPHX2PDE2ACACNA1HHCRTR1HCRTR2 | |
| SCHEMBL20061669 | 0.81 | PDE2A (0.44) | TP53EPHX2PDE2ACACNA1HHCRTR1 | |
| SCHEMBL6696266 | 0.81 | TP53 (0.41) | TP53TSHR | |
| SCHEMBL18181376 | 0.79 | PDE2A (0.43) | EPHX2PDE2ACACNA1HHCRTR1HCRTR2 | |
| SCHEMBL18174185 | 0.79 | EPHX2 (0.50) | EPHX2PDE2ACACNA1H | |
| SCHEMBL20128512 | 0.79 | EPHX2 (0.50) | EPHX2PDE2ACACNA1HP2RX7 | |
| SCHEMBL18174275 | 0.79 | EPHX2 (0.50) | EPHX2PDE2ACACNA1H | |
| SCHEMBL6601018 | 0.78 | TP53 (0.49) | TP53TSHRP2RX7 | |
| SCHEMBL6599643 | 0.77 | TSHR (0.56) | TP53TSHREPHX2PDE2A | |
| SCHEMBL20061666 | 0.77 | PDE2A (0.42) | EPHX2PDE2ACACNA1HHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152903-A1 | 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides | KUREHA CORPORATION (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1375483-A1 | 6-CHLORO-3-PYRIDYLMETHYLPROPYLAMINE DERIVATIVES, PREPARATION PROCESS THEREOF AND BACTERICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152903-A1 | 6-chloro-3-pyridylmethylpropylamine derivatives, preparation process thereof and bactericides | PGLS, TLR6, UROD | TP53 3860/4885TSHR 3142/4885EPHX2 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.