Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 4/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SLCO2A1 | Q92959 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18651340 | 0.90 | PDE4D (0.59) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL20061770 | 0.90 | PDE4D (0.59) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL18651338 | 0.90 | SLCO2A1 (0.67) | PTGFRTBXA2RPTGER2SLCO2A1MEN1 | |
| SCHEMBL19821586 | 0.88 | PTGFR (0.60) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL18651341 | 0.87 | PDE4D (0.59) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL18651339 | 0.87 | SLCO2A1 (0.67) | PTGFRPTGER2SLCO2A1MEN1KMT2A | |
| SCHEMBL13061506 | 0.84 | PTGFR (0.73) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL20069041 | 0.84 | PTGFR (0.58) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL1747671 | 0.83 | PTGFR (0.71) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 | |
| SCHEMBL3364894 | 0.83 | PTGFR (0.71) | PTGFRTBXA2RPTGER2ALDH1A1SLCO2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104350-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | Graybug Vision, Inc. (US) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104350-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | PTGIR, PTGIS, CA2 | PTGFR 24/4885TBXA2R 23/4885PTGER2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.