SCHEMBL20062368

SCHEMBL20062368

c1ccc2c(c1)-c1ccccc1-c1cc3cccnc3cc1-c1ccc(-n3c4ccccc4c4ccccc43)cc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
POLB P06746 3/20 0.39
PSMD14 O00487 1/20 0.39
TP53 P04637 1/20 0.39
MMP2 P08253 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP3A4 P08684 1/20 0.37
NPC1 O15118 2/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
PDGFRB P09619 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062354 1.00 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062364 1.00 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062357 1.00 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062356 1.00 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062360 1.00 ALDH1A1 (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL22929904 0.83 KDM4E (0.42) ALDH1A1KDM4EGAAATML3MBTL1
SCHEMBL16484366 0.83 MAPT (0.55) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062405 0.83 KDM4E (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062406 0.83 KDM4E (0.39) ALDH1A1KDM4EGAAMAPTPOLB
SCHEMBL20062398 0.83 KDM4E (0.39) ALDH1A1KDM4EGAAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10608185-B2 Organic electroluminescent materials and devices UNIVERAL DISPLAY CORPORATION (US) 2020-03-31 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed
US-20180108844-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180108844-A1 Organic Electroluminescent Materials and Devices SLCO4C1, SLCO2A1, SLCO2B1 ALDH1A1 1333/4885KDM4E 4299/4885GAA 2520/4885
US-10608185-B2 Organic electroluminescent materials and devices SLCO4C1, SLCO2A1, SLCO2B1 ALDH1A1 1333/4885KDM4E 4299/4885GAA 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.