SCHEMBL22929904

SCHEMBL22929904

c1ccc2c(c1)-c1ccc(-n3c4ccccc4c4ccccc43)cc1-c1cccnc1-c1ncccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTPRC P08575 2/20 0.40
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TDP2 O95551 1/20 0.37
NSD2 O96028 1/20 0.37
ABL1 P00519 1/20 0.37
PLCG1 P19174 1/20 0.37
CES1 P23141 1/20 0.37
PAX8 Q06710 1/20 0.37
RIN1 Q13671 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 1/20 0.37
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
PTPN13 Q12923 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929920 0.96 KDM4E (0.39) KDM4EATML3MBTL1PTPRCMEN1
SCHEMBL22930027 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTPRCMEN1
SCHEMBL22929955 0.91 ATM (0.35) KDM4EATML3MBTL1PTPRCMEN1
SCHEMBL22929975 0.90 KDM4E (0.34) KDM4EATML3MBTL1PTPRCMEN1
SCHEMBL22929946 0.89 KDM4E (0.43) KDM4EATML3MBTL1PTPRCGAA
SCHEMBL22930042 0.89 KDM4E (0.36) KDM4EATML3MBTL1PTPRCHIF1A
SCHEMBL18252520 0.85 L3MBTL1 (0.56) KDM4EATML3MBTL1PTPRCHIF1A
SCHEMBL26519426 0.85 L3MBTL1 (0.56) KDM4EATML3MBTL1PTPRCHIF1A
SCHEMBL17947698 0.85 L3MBTL1 (0.56) KDM4EATML3MBTL1PTPRCHIF1A
SCHEMBL22929899 0.85 KDM4E (0.36) KDM4EATML3MBTL1PTPRCTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910577-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910577-B2 Organic electroluminescent materials and devices CACNA2D2, ORC3, ANO2 KDM4E 1899/4885ATM 4018/4885L3MBTL1 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.