SCHEMBL20062882

SCHEMBL20062882

Cc1cccc(N2C(=C3N(c4cccc(C)n4)c4cc(-c5ccccc5)c(-c5ccccc5)cc4N3c3cccc(C)n3)N(c3cccc(C)n3)c3cc(-c4ccccc4)c(-c4ccccc4)cc32)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.45
HCRTR1 O43613 1/20 0.41
HCRTR2 O43614 1/20 0.41
TGFBR1 P36897 1/20 0.39
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
ALDH1A1 P00352 3/20 0.37
IRAK4 Q9NWZ3 2/20 0.36
MAPT P10636 3/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 3/20 0.35
ALOX5 P09917 1/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062892 0.85 RECQL (0.43) RECQLTGFBR1HTR3EHTR3BHTR3A
SCHEMBL20062881 0.82 RECQL (0.51) RECQLTGFBR1HTR3EHTR3BHTR3A
SCHEMBL20681918 0.80 HCRTR1 (0.43) RECQLHCRTR1HCRTR2TGFBR1HTR3E
SCHEMBL18905735 0.70 BACE1 (0.39) ALDH1A1RAB9ANPC1L3MBTL1ALOX5
SCHEMBL29562157 0.69 RECQL (0.62) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL5026395 0.69 RECQL (0.62) RECQLHTR3EHTR3BHTR3AHTR3D
SCHEMBL20062885 0.67 HPGD (0.34) L3MBTL1KDM4ETP53HPGDTSHR
SCHEMBL20062908 0.67 NOTUM (0.43) RECQLALDH1A1MAPTRAB9ANPC1
SCHEMBL15903364 0.67 RECQL (0.59) RECQLTGFBR1HTR3EHTR3BHTR3A
SCHEMBL31663552 0.66 TGFBR1 (0.53) TGFBR1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed