SCHEMBL20062885

SCHEMBL20062885

CC(C)c1cccc(N2/C(=C3/N(c4cccc(C(C)C)n4)c4ccc(-c5ccccc5)cc4N3c3cccc(C(C)C)n3)N(c3cccc(C(C)C)n3)c3cc(-c4ccccc4)ccc32)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
TYMS P04818 1/20 0.33
NR1H2 P55055 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
COMT P21964 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
PDE6D O43924 1/20 0.30
HSD11B1 P28845 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062892 0.82 RECQL (0.43) TYMSHSD11B1GAAL3MBTL1
SCHEMBL20681878 0.80 NR1H2 (0.34) HPGDHSD17B10LMNATP53TSHR
SCHEMBL18905721 0.71 MGLL (0.40) HPGDHTTRXRARXRBRXRG
SCHEMBL20062936 0.71 FLT3 (0.35) TYMSCOMTKDM4EGAAL3MBTL1
SCHEMBL20062913 0.70 GAA (0.36) HPGDHSD17B10LMNATSHRHTT
SCHEMBL18905746 0.69 ALDH1A1 (0.43) HPGDHSD17B10LMNAHTTTYMS
SCHEMBL19343013 0.68 HSP90AA1 (0.45) HPGDLMNAHTTESR1ESR2
SCHEMBL20062882 0.67 RECQL (0.45) HPGDHSD17B10TP53TSHRKDM4E
SCHEMBL20062920 0.67 RAB9A (0.38) HPGDHSD17B10LMNATP53TSHR
SCHEMBL20062879 0.67 MEN1 (0.39) LMNARXRARXRBCOMTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed