SCHEMBL20062896

SCHEMBL20062896

Cc1cc2c(cc1C)N(c1ccc(C(C)(C)C)nc1)C(=C1N(c3ccc(C(C)(C)C)nc3)c3cc(C)c(C)cc3N1c1ccc(C(C)(C)C)nc1)N2c1ccc(C(C)(C)C)nc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
MAPK14 Q16539 2/20 0.32
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
CDK8 P49336 1/20 0.31
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
CCR9 P51686 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062894 0.83 CA12 (0.35) HPGDCCR9
SCHEMBL20062902 0.80 MEN1 (0.31)
SCHEMBL20681909 0.79 MAPK13 (0.31) MAPK14MAPK13MAPK12MAPK11CDK8
SCHEMBL20062893 0.79 PDPK1 (0.35) HPGDCCR9
SCHEMBL20062938 0.78
SCHEMBL20062916 0.76 GAA (0.35) GAAHPGD
SCHEMBL20062890 0.74 TP53 (0.30)
SCHEMBL18905701 0.74 TSHR (0.41) HPGD
SCHEMBL20062869 0.73 TSHR (0.52) ELANECDK8GAAHPGD
SCHEMBL18905736 0.73 ELANE (0.48) ELANEGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed