SCHEMBL20062893

SCHEMBL20062893

CC(C)(C)c1ccc(-c2ccc3c(c2)N(c2ccc(C(C)(C)C)nc2)/C(=C2\N(c4ccc(C(C)(C)C)nc4)c4ccc(-c5ccc(C(C)(C)C)cc5)cc4N2c2ccc(C(C)(C)C)nc2)N3c2ccc(C(C)(C)C)nc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.35
KIF11 P52732 3/20 0.35
FLT3 P36888 1/20 0.34
CCR9 P51686 3/20 0.33
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
DGAT1 O75907 2/20 0.31
HSD17B2 P37059 1/20 0.30
LCK P06239 1/20 0.30
KIT P10721 1/20 0.30
SRC P12931 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062894 0.89 CA12 (0.35) CCR9HSD11B1ALDH1A1HTTMEN1
SCHEMBL18905690 0.84 KIF11 (0.40) PDPK1KIF11ALDH1A1TSHRKMT2A
SCHEMBL20062896 0.79 ELANE (0.33) CCR9HPGD
SCHEMBL20062902 0.77 MEN1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL19343014 0.75 HSP90AA1 (0.39) KIF11ALDH1A1HPGDKMT2ASMN1; SMN2
SCHEMBL18905679 0.73 CA9 (0.39) KIF11ALDH1A1MEN1HPGDTSHR
SCHEMBL18905684 0.73 CA9 (0.39) KIF11ALDH1A1MEN1HPGDTSHR
SCHEMBL12173602 0.73 KIF11 (0.53) KIF11ALDH1A1TSHRKMT2ACA12
SCHEMBL14062425 0.73 KIF11 (0.53) KIF11ALDH1A1TSHRKMT2ACA12
SCHEMBL20062898 0.73 CHRNB2 (0.40) MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 PDPK1 3236/4885KIF11 3941/4885FLT3 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.