SCHEMBL20062894

SCHEMBL20062894

CC(C)(C)c1ccc2c(c1)N(c1ccc(C(C)(C)C)nc1)/C(=C1\N(c3ccc(C(C)(C)C)nc3)c3ccc(C(C)(C)C)cc3N1c1ccc(C(C)(C)C)nc1)N2c1ccc(C(C)(C)C)nc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA9 Q16790 2/20 0.35
CA2 P00918 1/20 0.35
TP53 P04637 1/20 0.33
CCR9 P51686 3/20 0.33
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062893 0.89 PDPK1 (0.35) CA12CA9CCR9HSD11B1ALDH1A1
SCHEMBL20062896 0.83 ELANE (0.33) CCR9HPGD
SCHEMBL20062937 0.82 ALDH1A1 (0.31) ALDH1A1HPGDALOX15
SCHEMBL20062902 0.82 MEN1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL18905679 0.81 CA9 (0.39) CA12CA1CA9CA2ALDH1A1
SCHEMBL18905684 0.81 CA9 (0.39) CA12CA1CA9CA2ALDH1A1
SCHEMBL20062918 0.80 HPGD (0.32) CA12CA1CA9CA2ALDH1A1
SCHEMBL20062898 0.80 CHRNB2 (0.40) MEN1KMT2ANPSR1
SCHEMBL20681898 0.79 TP53 (0.33) CA12CA1CA9CA2TP53
SCHEMBL20062895 0.77 ALDH1A1 (0.44) CCR9ALDH1A1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed