SCHEMBL20062903

SCHEMBL20062903

c1ccc2c(c1)N(c1ccncc1)C(=C1N(c3ccncc3)c3ccccc3N1c1ccncc1)N2c1ccncc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
LMNA P02545 1/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
EED O75530 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
THPO P40225 1/20 0.40
NOTUM Q6P988 1/20 0.39
MAPK1 P28482 1/20 0.38
CHKA P35790 1/20 0.38
AR P10275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17383504 0.79 ALDH1A1 (0.46) BCHEMEN1KMT2ANPSR1ALDH1A1
SCHEMBL20062908 0.78 NOTUM (0.43) BCHELMNAMEN1KMT2ANPSR1
SCHEMBL17123078 0.77 HTT (0.53) BCHELMNAALDH1A1CYP1A2CYP3A4
SCHEMBL20062887 0.76 HTT (0.56) ALDH1A1CYP3A4MAPK1ARMAPT
SCHEMBL20062905 0.76 BCHE (0.42) BCHELMNAMEN1KMT2ANPSR1
SCHEMBL20062933 0.74 ATM (0.39) TLR9
SCHEMBL27967964 0.74 CDK8 (0.43) BCHELMNAMEN1KMT2ANPSR1
SCHEMBL17383346 0.71 MGLL (0.46) LMNAMEN1KMT2ANPSR1ALDH1A1
SCHEMBL17123064 0.71 ALDH1A1 (0.48) BCHELMNAMEN1KMT2ANPSR1
SCHEMBL20908636 0.71 BCHE (0.42) BCHELMNAMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed