SCHEMBL20062927

SCHEMBL20062927

c1cnc(N2C(=C3N(c4ncccn4)c4ccccc4N3c3ncccn3)N(c3ncccn3)c3ccccc32)nc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.42
GAA P10253 1/20 0.42
LMNA P02545 3/20 0.39
MAPT P10636 1/20 0.39
TLR9 Q9NR96 1/20 0.37
POLB P06746 3/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36
CCR8 P51685 1/20 0.36
METAP1 P53582 1/20 0.36
BLM P54132 1/20 0.36
HIF1A Q16665 1/20 0.36
DOHH Q9BU89 1/20 0.36
P4HTM Q9NXG6 1/20 0.36
NPC1 O15118 2/20 0.35
ALDH1A1 P00352 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062944 0.81 TLR9 (0.34) TLR9
SCHEMBL20062878 0.76 SMN1; SMN2 (0.53) HTTGAALMNAPOLBKDM4E
SCHEMBL20062921 0.75 KDM4E (0.33) POLBKDM4EBLMNPC1ALDH1A1
SCHEMBL28577558 0.73 KDM1A (0.50) HTTGAALMNAPOLBALDH1A1
SCHEMBL20062943 0.71 TLR9 (0.34) TLR9
SCHEMBL20681830 0.70 GAA (0.42) HTTGAALMNAMAPTPOLB
SCHEMBL20908633 0.70 GAA (0.35) HTTGAALMNAMAPTPOLB
SCHEMBL20062929 0.69 TLR9 (0.32) TLR9
SCHEMBL20062939 0.69 RPS6KA5 (0.42) TLR9CYP1A2RPS6KA5SMN1; SMN2
SCHEMBL20062903 0.68 BCHE (0.46) LMNAMAPTTLR9KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed