SCHEMBL20062959

SCHEMBL20062959

Cc1ccc(N2C(=C3N(c4ccc(C)s4)c4cc(C)c(C)cc4N3c3ccc(C)s3)N(c3ccc(C)s3)c3cc(C)c(C)cc32)s1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062964 0.82 ALDH1A1 (0.33) NPC1MAPTCASP3RAB9ASMN1; SMN2
SCHEMBL20062961 0.78 MAPK1 (0.33)
SCHEMBL19343012 0.69 CYP2A6 (0.40)
SCHEMBL20071953 0.67 SKP2 (0.33) NPC1RAB9A
SCHEMBL18905744 0.64 MGLL (0.52) MAPTCASP3SMN1; SMN2SENP8SENP7
SCHEMBL18905736 0.64 ELANE (0.48) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL18905740 0.64 KMT2A (0.50) NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL23743459 0.63 TP53 (0.33) MAPT
SCHEMBL24715765 0.63
SCHEMBL20062905 0.61 BCHE (0.42) NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed