Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | KCNK3 | O14649 | 10/20 | 0.65 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074245 | 0.89 | KCNK3 (0.66) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL20073121 | 0.84 | MAPT (0.67) | MEN1KMT2AKCNK3KCNK9RAB9A | |
| SCHEMBL20064060 | 0.84 | RAB9A (0.62) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL12847636 | 0.84 | KMT2A (0.76) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL7293743 | 0.82 | KCNK3 (0.86) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL22025451 | 0.81 | MEN1 (0.62) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL4253897 | 0.80 | KCNK3 (0.93) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL18775273 | 0.80 | MEN1 (0.69) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL22025458 | 0.80 | MEN1 (0.69) | MEN1KMT2ARXFP1KCNK3KCNK9 | |
| SCHEMBL20064059 | 0.80 | KCNK3 (0.77) | MEN1KMT2ARXFP1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105528-A1 | PREPARATION AND USE OF NOVEL PROTEIN KINASE INHIBITORS | BRANDEIS UNIVERSITY | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105528-A1 | PREPARATION AND USE OF NOVEL PROTEIN KINASE INHIBITORS | MAP3K20, MAP3K19, MAP3K5 | MEN1 2205/4885KMT2A 1776/4885RXFP1 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.