Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PDE5A | O76074 | 1/20 | 0.60 |
| ▸ | PDE1A | P54750 | 1/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.60 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 6/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363225 | 0.85 | POLB (0.75) | RAB9ANPC1TP53NFKB1NFKB2 | |
| SCHEMBL20073173 | 0.84 | MAPT (0.62) | RAB9ATP53KCNK3MEN1KMT2A | |
| SCHEMBL20064056 | 0.84 | MEN1 (0.66) | RAB9ANPC1TP53NFKB1NFKB2 | |
| SCHEMBL8460899 | 0.81 | PKM (0.64) | RAB9ANPC1TP53SMN1; SMN2MEN1 | |
| SCHEMBL9486281 | 0.81 | SMN1; SMN2 (0.64) | RAB9ANPC1TP53SMN1; SMN2MEN1 | |
| SCHEMBL11807944 | 0.80 | CTNNB1 (0.55) | RAB9ANPC1KCNK3L3MBTL1LMNA | |
| SCHEMBL7293743 | 0.78 | KCNK3 (0.86) | RAB9ANPC1TP53NFKB1NFKB2 | |
| SCHEMBL14363190 | 0.78 | KCNK3 (0.68) | RAB9ANPC1TP53SMN1; SMN2KCNK3 | |
| SCHEMBL259430 | 0.77 | NPC1 (1.00) | RAB9ANPC1TP53NFKB1NFKB2 | |
| SCHEMBL25950796 | 0.77 | RARA (0.53) | RAB9ATP53SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180105528-A1 | PREPARATION AND USE OF NOVEL PROTEIN KINASE INHIBITORS | BRANDEIS UNIVERSITY | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105528-A1 | PREPARATION AND USE OF NOVEL PROTEIN KINASE INHIBITORS | MAP3K20, MAP3K19, MAP3K5 | RAB9A 1291/4885NPC1 3099/4885TP53 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.