Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9606612 | 0.95 | CTSK (0.45) | CTSKCA1CA2CA7TSHR | |
| SCHEMBL28175055 | 0.95 | CTSK (0.45) | CTSKCA1CA2CA7TSHR | |
| SCHEMBL23487152 | 0.89 | CTSK (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL31362911 | 0.89 | CTSK (0.43) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL20064346 | 0.87 | CTSK (0.42) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL16512842 | 0.85 | CTSK (0.41) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL27542782 | 0.84 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL22838055 | 0.84 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL211543 | 0.84 | CA2 (0.43) | CTSKCA1CA2CA7TSHR | |
| SCHEMBL211542 | 0.84 | CA2 (0.43) | CTSKCA1CA2CA7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |