SCHEMBL200641

SCHEMBL200641

Cl[Si](Cl)(Cl)C1CC2C=CC1C2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
EPHX2 P34913 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393789 1.00 KDM4E (0.38) KDM4ELMNAALDH1A1GAATDP1
Toluene SCHEMBL7034592 0.82 KDM4E (0.38) KDM4ELMNAALDH1A1TDP1
SCHEMBL13609496 0.81
SCHEMBL30205639 0.81 KDM4E (0.31) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL200393 0.81 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL6063873 0.76
SCHEMBL6064141 0.76
SCHEMBL4603761 0.76
SCHEMBL6064305 0.76
SCHEMBL201515 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363967-B1 IMPROVED FIBER SUBSTRATE ADHESION TO ELASTOMERIC SUBSTRATES LORD CORP (US) 2006-04-12 EP claimed
JP-2004519566-A 2004-07-02 JP claimed
EP-1363967-A2 IMPROVED FIBER SUBSTRATE ADHESION AND COATINGS BY METATHESIS POLYMERIZATION Lord Corporation (US) 2003-11-26 EP claimed
WO-2002077078-A2 IMPROVED FIBER SUBSTRATE ADHESION AND COATINGS BY METATHESIS POLYMERIZATION LORD CORPORATION (US) 2002-10-03 WO claimed
EP-0258418-A4 ELASTOMER-PLASTIC BLENDS. EXXON RESEARCH ENGINEERING CO (US) 1989-06-26 EP claimed
EP-0258418-A1 ELASTOMER-PLASTIC BLENDS ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1988-03-09 EP claimed
EP-0240638-A2 Olefinic chlorosilane and olefinic halide functional group containing polymers and method of forming the same EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-10-14 EP claimed
WO-1987005312-A1 ELASTOMER-PLASTIC BLENDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-09-11 WO claimed
WO-1987003606-A1 OLEFINIC CHLOROSILANE AND OLEFINIC HALIDE FUNCTIONAL GROUP CONTAINING POLYMERS AND METHOD OF FORMING THE SAME EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-06-18 WO claimed
JP-63199251-A None JP disclosed
EP-4617314-A1 COMPOSITION FOR FORMING A MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS, METHOD FOR FORMING A MOLDED PRODUCT, AND MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS Daikin Industries, Ltd. (JP) 2025-09-17 EP disclosed
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-08-05 US disclosed
US-20220219155-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2022-07-14 US disclosed
US-11331656-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-05-17 US disclosed
EP-0240638-A2 Olefinic chlorosilane and olefinic halide functional group containing polymers and method of forming the same EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-10-14 EP disclosed
WO-1987005312-A1 ELASTOMER-PLASTIC BLENDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-09-11 WO disclosed
WO-1987003606-A1 OLEFINIC CHLOROSILANE AND OLEFINIC HALIDE FUNCTIONAL GROUP CONTAINING POLYMERS AND METHOD OF FORMING THE SAME EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-06-18 WO disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4153765-A Curable composition containing EPM or EPDM interpolymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1979-05-08 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11331656-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis PPOX, CYBA, CYBB KDM4E 3807/4885LMNA 4173/4885ALDH1A1 1395/4885
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis PPOX, CYBA, CYBB KDM4E 3807/4885LMNA 4173/4885ALDH1A1 1395/4885
US-20220219155-A1 Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis PPOX, CYBA, CYBB KDM4E 3807/4885LMNA 4173/4885ALDH1A1 1395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.