SCHEMBL200393

SCHEMBL200393

C[Si](C)(Cl)C1CC2C=CC1C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201645 0.86 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL3267075 0.81 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL29393789 0.81 KDM4E (0.38) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL16773667 0.81 KDM4E (0.33) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL200641 0.81 KDM4E (0.38) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL199783 0.79
SCHEMBL30205639 0.77 KDM4E (0.31) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6902908 0.77 KDM4E (0.32) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6836633 0.77 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1
SCHEMBL6904497 0.77 KDM4E (0.35) KDM4EALDH1A1LMNAGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
EP-1711542-B1 DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF PROMERUS LLC (US) 2010-06-09 EP disclosed
US-7691919-B2 Dental materials based on ROMP composites IVOCLAR VIVADENT AG (LI) 2010-04-06 US disclosed
EP-1266912-B1 (Meth)acryloyl group-modified ethylene-alpha-olefin copolymer, production method thereof and rubber composition JSR CORP (JP) 2008-12-17 EP disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-7378456-B2 Directly photodefinable polymer compositions and methods thereof PROMERUS LLC (US) 2008-05-27 US disclosed
EP-1555290-B1 Dental materials based on ROMP-composites IVOCLAR VIVADENT AG (LI) 2007-06-27 EP disclosed
US-6197984-B1 Method for the preparation of copolymers of ethylene/norbornene-type monomers with nickel catalysts THE B. F. GOODRICH COMPANY 2001-03-06 US disclosed
EP-0988331-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 2000-03-29 EP disclosed
EP-0988330-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS THE B.F. GOODRICH COMPANY (US) 2000-03-29 EP disclosed
US-6031058-A POLYMERS OF THE INVENTION INCLUDE POLYCYCLIC REPEAT UNITS THAT CONTAIN PENDANT SILYL FUNCTIONAL GROUPS THE B.F. GOODRICH COMPANY (US) 2000-02-29 US disclosed
US-5929181-A Method for preparation of copolymers of ethylene/norbornene-type monomers with nickel catalysts THE B.F.GOODRICH CO. (US) 1999-07-27 US disclosed
US-5912313-A MOLDINGS, COATINGS, ADHESIVES, MEMBRANES; OXIDATION, HEAT AND CHEMICAL RESISTANCE; DIELECTRICS, INTEGRATED CIRCUITS THE B. F. GOODRICH COMPANY (US) 1999-06-15 US disclosed
WO-1998056839-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS THE B.F. GOODRICH COMPANY (US) 1998-12-17 WO disclosed
WO-1998056837-A1 METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH NICKEL CATALYSTS THE B.F. GOODRICH COMPANY (US) 1998-12-17 WO disclosed
US-4153765-A Curable composition containing EPM or EPDM interpolymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1979-05-08 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed