Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475631 | 0.81 | CYP1A2 (0.36) | CYP1A2SHBG | |
| SCHEMBL29111084 | 0.79 | CYP1A2 (0.39) | CYP1A2SHBG | |
| SCHEMBL10387752 | 0.76 | CYP1A2 (0.41) | CYP1A2SHBG | |
| SCHEMBL2991590 | 0.76 | CYP1A2 (0.41) | CYP1A2SHBG | |
| SCHEMBL7526068 | 0.76 | CYP1A2 (0.41) | CYP1A2SHBG | |
| SCHEMBL28261065 | 0.74 | CYP1A2 (0.39) | CYP1A2SHBG | |
| SCHEMBL20350217 | 0.73 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL8029378 | 0.73 | CYP1A2 (0.42) | CYP1A2SHBG | |
| SCHEMBL28578100 | 0.73 | CYP1A2 (0.38) | CYP1A2SHBG | |
| SCHEMBL11981967 | 0.73 | CYP1A2 (0.38) | CYP1A2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |