SCHEMBL2991590

SCHEMBL2991590

CCCC(C)(C1CCCCC1)C(C)(CCC)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
SHBG P04278 1/20 0.32
CHRM2 P08172 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
KCNH2 Q12809 1/20 0.31
SSTR4 P31391 1/20 0.31
CNR1 P21554 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174328 0.89 CYP1A2 (0.37) CYP1A2
SCHEMBL10387752 0.80 CYP1A2 (0.41) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL7526068 0.80 CYP1A2 (0.41) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL3000305 0.79 CYP1A2 (0.39) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL28261065 0.78 CYP1A2 (0.39) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL8029378 0.77 CYP1A2 (0.42) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL20350217 0.77 CYP1A2 (0.37) CYP1A2MEN1ALDH1A1LMNAALOX12
SCHEMBL28578100 0.76 CYP1A2 (0.38) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL20064600 0.76 CYP1A2 (0.38) CYP1A2SHBG
SCHEMBL2994171 0.76 CYP1A2 (0.38) CYP1A2SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed