SCHEMBL8029378

SCHEMBL8029378

CCCC(CCC)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
SHBG P04278 1/20 0.33
CHRM2 P08172 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
KCNH2 Q12809 1/20 0.32
ADH1A P07327 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605998 0.90 CYP1A2 (0.39) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL28259395 0.87 CYP1A2 (0.34) CYP1A2
SCHEMBL27910012 0.81 ADH1A (0.35) CYP1A2ADH1A
SCHEMBL29102614 0.79 SIGMAR1 (0.39) CYP1A2
SCHEMBL6318304 0.78 CYP1A2 (0.40) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL10779865 0.78 CYP1A2 (0.40) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL12504404 0.77 NAAA (0.36)
SCHEMBL10942478 0.77 CYP1A2 (0.41) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL7526068 0.77 CYP1A2 (0.41) CYP1A2SHBGCHRM2CYP2D6CHRM1
SCHEMBL16933912 0.77 CYP1A2 (0.41) CYP1A2SHBGCHRM2CYP2D6CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed