SCHEMBL20064688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20064747	0.86	ALDH1A1 (0.52)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL18198492	0.80	ALDH1A1 (0.50)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064720	0.80	MAPT (0.59)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064696	0.80	HPGD (0.48)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064719	0.80	MAPT (0.43)	ALDH1A1KDM4EGAAHPGDMAPT
	SCHEMBL18198346	0.79	MAPT (0.47)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL18198477	0.79	MAPT (0.45)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064682	0.79	MAPT (0.45)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064708	0.78	MAPT (0.45)	ALDH1A1KDM4EGAAHPGDKMT2A
	SCHEMBL20064726	0.77	NPC1 (0.53)	ALDH1A1KDM4EGAAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.