Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18180496 | 0.83 | NOTUM (0.38) | CYP11B1SMN1; SMN2IDH1CYP11B2NOTUM | |
| SCHEMBL14198665 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1RAB9ARIPK1 | |
| SCHEMBL1979451 | 0.77 | SMN1; SMN2 (0.43) | CYP11B1SMN1; SMN2IDH1ALDH1A1RAB9A | |
| SCHEMBL14674651 | 0.77 | SMN1; SMN2 (0.43) | CYP11B1SMN1; SMN2IDH1ALDH1A1RAB9A | |
| SCHEMBL20066498 | 0.77 | MEN1 (0.54) | CYP11B1SMN1; SMN2ALDH1A1RAB9ATDP1 | |
| SCHEMBL23189096 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ARIPK1RET | |
| SCHEMBL28670401 | 0.76 | CYP11B1 (0.66) | CYP11B1SMN1; SMN2ALDH1A1RAB9ATDP1 | |
| SCHEMBL15964719 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ARIPK1BRD4RET | |
| SCHEMBL23188862 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ARIPK1RET | |
| SCHEMBL17321301 | 0.74 | SMN1; SMN2 (0.49) | CYP11B1SMN1; SMN2ALDH1A1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180104220-A1 | IMIDAZOLE COMPOUND | MAPT, SLC10A2, SLC5A11 | CYP11B1 69/4885SMN1; SMN2 775/4885IDH1 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.