SCHEMBL2006727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14085381	0.82	CYP11B1 (0.49)	CYP19A1CYP2C9CYP11B1CYP11B2SPR
	SCHEMBL12572460	0.81	NPC1 (0.44)	CYP19A1CYP2C9CYP11B1CYP11B2MAPT
	SCHEMBL7736697	0.79	CA12 (0.49)	CA12CA9POLBKMT2A
	SCHEMBL1727533	0.73	ESRRA (0.40)	MAPTESR1ESR2HSD17B1HSD17B2
	SCHEMBL2008964	0.71	CYP11B1 (0.45)	CYP19A1CYP2C9CYP11B1CYP11B2HSD17B1
	SCHEMBL31196446	0.70	KDM4E (0.51)	MAPTRXFP1POLB
	SCHEMBL5266188	0.69	MAPT (0.38)	CYP19A1CYP2C9CYP11B1CYP11B2MAPT
	SCHEMBL1727325	0.69	HSD17B1 (0.41)	MAPTESR1ESR2MEN1POLB
	SCHEMBL21526697	0.69	ESRRA (0.55)	CA12CA9ESR1ESR2
	SCHEMBL17247304	0.68	CYP11B2 (0.69)	CYP19A1CYP2C9CYP11B1CYP11B2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.