Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493652 | 0.84 | ADAM17 (0.40) | DPP4DPP8DPP9MEN1KMT2A | |
| SCHEMBL21126099 | 0.83 | CA2 (0.37) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13857685 | 0.82 | MEN1 (0.33) | DPP4DPP8DPP9MEN1KMT2A | |
| SCHEMBL25412477 | 0.82 | MME (0.43) | DPP4DPP8DPP9MEN1KMT2A | |
| SCHEMBL25748776 | 0.82 | ELANE (0.33) | ELANECA12CA1CA2MMP1 | |
| SCHEMBL27376558 | 0.82 | ELANE (0.33) | DPP4ELANECA12CA1CA2 | |
| SCHEMBL25412479 | 0.82 | MME (0.43) | DPP4DPP8DPP9MEN1KMT2A | |
| SCHEMBL13253551 | 0.81 | MME (0.40) | CASP1BACE1 | |
| SCHEMBL31631405 | 0.81 | MME (0.40) | CASP1BACE1 | |
| SCHEMBL22829566 | 0.80 | KMT2A (0.39) | DPP4DPP8DPP9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069375-A1 | NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2018-04-19 | — | — | WO | disclosed |