Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | CASR | P41180 | 7/20 | 0.46 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006574 | 0.73 | ERN1 (0.40) | NR3C1PGRCASRMMEL1ERN1 | |
| SCHEMBL4971998 | 0.72 | CASR (0.50) | NR3C1PGRCASRMMEL1ERN1 | |
| Hydrochloric Acid SCHEMBL2006333 | 0.71 | CASR (0.49) | NR3C1PGRCASRMMEL1ERN1 | |
| SCHEMBL2155522 | 0.71 | CTSL (0.74) | — | |
| SCHEMBL2009504 | 0.70 | CASR (0.49) | NR3C1PGRCASRMMEL1ERN1 | |
| SCHEMBL2009918 | 0.70 | CASR (0.49) | NR3C1PGRCASRMMEL1ERN1 | |
| SCHEMBL2008074 | 0.68 | NR3C1 (0.54) | NR3C1PGRCASR | |
| SCHEMBL2005613 | 0.67 | NR3C1 (0.62) | NR3C1PGRCASR | |
| SCHEMBL2005610 | 0.67 | NR3C1 (0.62) | NR3C1PGRCASR | |
| SCHEMBL7875700 | 0.65 | ERN1 (0.50) | NR3C1PGRMMEL1ERN1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |