Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975680 | 0.84 | HTR2A (0.63) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL16453918 | 0.83 | HTR2A (0.57) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL3037119 | 0.83 | HTR2A (0.68) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL25189373 | 0.83 | HTR2A (0.65) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL20467732 | 0.83 | HTR2A (0.54) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL17856871 | 0.82 | HTR2A (0.57) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL5827968 | 0.81 | HTR2A (0.80) | HTR2AALDH1A1MAPK1L3MBTL1HTT | |
| SCHEMBL20467625 | 0.81 | ALDH1A1 (0.65) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL29878239 | 0.81 | ALDH1A1 (0.60) | HTR2AALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL19733671 | 0.80 | ALDH1A1 (0.59) | HTR2AALDH1A1MAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011135-A2 | MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2018069375-A1 | NON-LINEAR SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2018-04-19 | — | — | WO | disclosed |