Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17856871 | 0.90 | HTR2A (0.57) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL6648196 | 0.88 | HTR2A (0.70) | ALDH1A1HTR2AMAPTMAPK1L3MBTL1 | |
| SCHEMBL3037119 | 0.83 | HTR2A (0.68) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL25189373 | 0.83 | HTR2A (0.65) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL14148578 | 0.82 | KMT2A (0.48) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL5827968 | 0.81 | HTR2A (0.80) | ALDH1A1HTR2AHTTMAPK1L3MBTL1 | |
| SCHEMBL20067655 | 0.81 | HTR2A (0.56) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL29878239 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL19733671 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HTR2AMAPTMEN1KMT2A | |
| SCHEMBL18391331 | 0.79 | HTR2A (0.66) | ALDH1A1HTR2AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637494-B2 | Method for producing peptide containing non-natural amino acid | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2026-05-26 | — | — | US | disclosed |
| US-20230069218-A1 | METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-03-02 | — | — | US | disclosed |
| EP-4074829-A1 | METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-10-19 | — | — | EP | disclosed |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-06 | — | — | US | disclosed |
| WO-2018143145-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | 中外製薬株式会社 | 2018-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637494-B2 | Method for producing peptide containing non-natural amino acid | MRPL21, RPL21, RPL30 | ALDH1A1 4795/4885HTR2A 4734/4885MAPT 3601/4885 |
| US-20230069218-A1 | METHOD FOR PRODUCING PEPTIDE CONTAINING NON-NATURAL AMINO ACID | MRPL21, RPL41, RPL21 | ALDH1A1 4179/4885HTR2A 4654/4885MAPT 4281/4885 |
| US-20200040372-A1 | METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM | AARS1, NSUN3, RNGTT | ALDH1A1 4757/4885HTR2A 3080/4885MAPT 4068/4885 |
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | VIP, SLC7A1, TRPV1 | ALDH1A1 4817/4885HTR2A 34/4885MAPT 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.