SCHEMBL20068081 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	ACMSD	Q8TDX5	8/20	0.67

▸	KMT2A	Q03164	2/20	0.39

▸	GAA	P10253	1/20	0.36

▸	GFER	P55789	1/20	0.36

▸	NFE2L2	Q16236	2/20	0.34

▸	KDM4E	B2RXH2	2/20	0.34

▸	POLB	P06746	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	CYP19A1	P11511	1/20	0.32

▸	CYP1A1	P04798	1/20	0.32

▸	CYP1A2	P05177	1/20	0.32

▸	CYP1B1	Q16678	1/20	0.32

▸	LMNA	P02545	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23696631	0.92	ACMSD (0.70)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL29529176	0.89	ACMSD (0.84)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20068211	0.89	ACMSD (0.69)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20068050	0.89	ACMSD (0.84)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20137807	0.89	ACMSD (0.84)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20068060	0.87	ACMSD (0.64)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20068152	0.87	ACMSD (0.69)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20068069	0.86	ACMSD (0.68)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL20138076	0.86	ACMSD (0.68)	ACMSDKMT2AGAAGFERNFE2L2
SCHEMBL29528851	0.86	ACMSD (0.68)	ACMSDKMT2AGAAGFERNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018069532-A1	INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE	TES PHARMA S.R.L. (IT)	2018-04-19	—	—	WO	disclosed