Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 8/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 7/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008990 | 0.83 | ABCB1 (0.39) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3583727 | 0.83 | ABCB1 (0.38) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL2006871 | 0.76 | ABCB1 (0.41) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3601136 | 0.74 | TP53 (0.43) | ABCB1CYP3A4ALOX15 | |
| SCHEMBL3601953 | 0.72 | ABCB1 (0.43) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3602288 | 0.71 | NPC1 (0.41) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3596795 | 0.68 | L3MBTL1 (0.39) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3599146 | 0.67 | KCNE1 (0.40) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3599142 | 0.67 | KCNE1 (0.40) | ABCB1KCNA5KCNE1KCNQ1CYP3A4 | |
| SCHEMBL2008987 | 0.67 | ABCB1 (0.42) | ABCB1KCNE1KCNQ1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964623-B2 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2011-06-21 | — | — | US | disclosed |