Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147711 | 0.81 | RET (0.38) | RET | |
| SCHEMBL20278453 | 0.63 | HSD11B1 (0.40) | — | |
| SCHEMBL16220913 | 0.62 | MAPK1 (0.44) | — | |
| SCHEMBL25057848 | 0.61 | HSD11B1 (0.41) | — | |
| SCHEMBL31082582 | 0.61 | HSD11B1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28718286 | 0.60 | HSD11B1 (0.40) | — | |
| SCHEMBL17700277 | 0.57 | NUDT1 (0.42) | PRKCB | |
| SCHEMBL12827199 | 0.57 | CCNT1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL18764595 | 0.56 | KDM4E (0.39) | — | |
| SCHEMBL24618308 | 0.56 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071454-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS | ANDREWS STEVEN W (US) | 2018-04-19 | — | — | WO | disclosed |