SCHEMBL2007034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2006258	0.78	NR3C1 (0.41)	MAPTMAPK1TDP1L3MBTL1SMN1; SMN2
	SCHEMBL14085312	0.78	CYP11B1 (0.42)	MAPTMAPK1TDP1L3MBTL1MRGPRX4
	SCHEMBL8531760	0.75	LMNA (0.43)	MAPTMAPK1TDP1L3MBTL1STAT3
	SCHEMBL2003613	0.73	MAPK14 (0.44)	MRGPRX4S1PR5PTGER1
	SCHEMBL2003916	0.73	S1PR5 (0.40)	MAPTSMN1; SMN2MRGPRX4POLBCYP11B1
	SCHEMBL1014598	0.73	ROCK1 (0.53)	MAPTMAPK1TDP1L3MBTL1MRGPRX4
	SCHEMBL5069111	0.73	MRGPRX4 (0.44)	STAT3HTTSMN1; SMN2MRGPRX4CYP2C9
	SCHEMBL29254805	0.73	MRGPRX4 (0.49)	MAPTMAPK1TDP1L3MBTL1MRGPRX4
	SCHEMBL14085379	0.73	MAPK14 (0.41)	MAPTSMN1; SMN2MRGPRX4LMNAPOLB
	SCHEMBL27503015	0.72	MAPT (0.41)	MAPTMAPK1TDP1L3MBTL1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.