SCHEMBL2007095

SCHEMBL2007095

O=C1C=CC2=CC=NCC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22123080 0.65
SCHEMBL4890519 0.62 ALDH1A1 (0.32)
SCHEMBL8195864 0.60 ALDH1A1 (0.35)
SCHEMBL8329529 0.60
SCHEMBL592447 0.59 MAOA (0.54)
SCHEMBL18342516 0.58 ALDH1A1 (0.32)
SCHEMBL30336930 0.57 ALDH1A1 (0.30)
SCHEMBL20892103 0.56
SCHEMBL21807200 0.56
SCHEMBL21643679 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190194138-A1 7H- azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof UNIV HUNAN CHINESE MEDICINE (CN) 2019-06-27 US claimed
EP-3212634-A1 COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE OREGON STATE UNIVERSITY (US) 2017-09-06 EP claimed
WO-2016069780-A1 COMPOUNDS AND METHODS TO SUPPRESS AUTOIMMUNE RESPONSE OREGON STATE UNIVERSITY (US) 2016-05-06 WO claimed
EP-2032141-A1 INHIBITORS OF JANUS KINASES Merck & Co., Inc. (US) 2009-03-11 EP claimed
WO-2007145957-A1 INHIBITORS OF JANUS KINASES MERCK & CO., INC. (US) 2007-12-21 WO claimed
WO-2005105814-A1 TETRACYCLIC INHIBITORS OF JANUS KINASES INCYTE CORPORATION (US) 2005-11-10 WO claimed
US-5925336-A Aqueous nail coating composition containing copolymerized colorants EASTMAN CHEMICAL COMPANY (US) 1999-07-20 US claimed
US-5744129-A Aqueous lip gloss and cosmetic compositions containing colored sulfopolyesters EASTMAN CHEMICAL COMPANY 1998-04-28 US claimed
US-5735907-A COLORANT REACTED INTO OR ONTO POLYMER BACKBONE CLAIROL, INC. (US) 1998-04-07 US claimed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP claimed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
JP-52151320-A None JP disclosed
EP-4688959-A2 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING Illumina, Inc. (US) 2026-02-11 EP disclosed
US-20240327910-A1 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING ILLUMINA, INC. 2024-10-03 US disclosed
WO-2024206407-A2 NAPHTHALIMIDE DYES AND USES IN NUCLEIC ACID SEQUENCING ILLUMINA, INC. (US) 2024-10-03 WO disclosed
US-4618555-A PHOTOSENSITIVITY; DURABILITY MITSUBISHI CHEMICAL IND., LTD. (JP) 1986-10-21 US disclosed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP disclosed
EP-0106430-A2 Isoquinoline derivatives as immuno-regulators ELI LILLY AND COMPANY (US) 1984-04-25 EP disclosed
JP-S52151320-A 3,4-DICHLORO-7H-BENZO(DE)-PYRAZOLO(5,1-A)ISOQUINOLINE-7-ONE DERIVATIVE MITSUBISHI CHEM IND LTD 1977-12-15 JP disclosed