SCHEMBL20071773

SCHEMBL20071773

CC(C)(C)c1ccc2c(c1)N(c1ccc(C(C)(C)C)s1)C(C1N(c3ccc(C(C)(C)C)s3)c3ccc(C(C)(C)C)cc3N1c1ccc(C(C)(C)C)s1)N2c1ccc(C(C)(C)C)s1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20071775 0.84 MAPK1 (0.32) MAPK1KMT2A
SCHEMBL20062963 0.81 MAPT (0.31) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL20071774 0.79 AR (0.38) ALDH1A1HPGDMAPK1
SCHEMBL20681894 0.69 ALDH1A1 (0.33) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL18911705 0.68 MAPT (0.33) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL20072095 0.68 HCRTR1 (0.42) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL20681889 0.68 KIF11 (0.43) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL20071768 0.68 SCN10A (0.33) MAPTSMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL20071952 0.68 RXRB (0.32)
SCHEMBL20071947 0.67 SCN10A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 MAPT 3694/4885SMN1; SMN2 2289/4885ALDH1A1 395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.