SCHEMBL20071844

SCHEMBL20071844

CC(C)(C)c1ccc2c(c1)N(c1ccc3ccccc3c1)C(C1N(c3ccc4ccccc4c3)c3ccc(C(C)(C)C)cc3N1c1ccc3ccccc3c1)N2c1ccc2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR5A P47898 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
HSP90AA1 P07900 1/20 0.36
RIPK2 O43353 1/20 0.35
SLC6A2 P23975 5/20 0.35
SLC6A4 P31645 5/20 0.35
SLC6A3 Q01959 4/20 0.35
CYP1A2 P05177 3/20 0.34
CYP2C19 P33261 3/20 0.34
CYP2C9 P11712 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 1/20 0.34
RAB9A P51151 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20072023 0.89 KCNH2 (0.38) HTR3ARIPK2RAB9AALDH1A1HPGD
SCHEMBL20071761 0.88 KCNH2 (0.37) HTR3AHSP90AA1RIPK2RAB9AALDH1A1
SCHEMBL20071827 0.83 KCNH2 (0.36) ALDH1A1HPGD
SCHEMBL17786071 0.82 HSP90AA1 (0.46) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL20071770 0.81 CYP2A6 (0.50) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL19355007 0.79 RAB9A (0.45) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL19342998 0.79 HSP90AA1 (0.42) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL20072051 0.79 UGT2B7 (0.41) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL20071842 0.78 CYP1A2 (0.50) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL18911905 0.77 CYP2C9 (0.37) CYP2C9SMN1; SMN2CYP3A4RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed