SCHEMBL20071827

SCHEMBL20071827

Cc1cc2c(cc1C)N(c1ccc3cc(C(C)(C)C)ccc3c1)C(C1N(c3ccc4cc(C(C)(C)C)ccc4c3)c3cc(C)c(C)cc3N1c1ccc3cc(C(C)(C)C)ccc3c1)N2c1ccc2cc(C(C)(C)C)ccc2c1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.36
NR1I2 O75469 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
TSHR P16473 1/20 0.31
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20072023 0.87 KCNH2 (0.38) KCNH2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL20071844 0.83 HTR3A (0.37) ALDH1A1HPGD
SCHEMBL20071761 0.83 KCNH2 (0.37) KCNH2ALDH1A1HPGDALOX15HSD17B10
SCHEMBL20071978 0.81 TSHR (0.50) NR1I2ALDH1A1NR1H4TSHRCA9
SCHEMBL19355007 0.80 RAB9A (0.45) ALDH1A1TDP1
SCHEMBL19343004 0.79 KCNH2 (0.37) KCNH2NR1I2ALDH1A1HPGDALOX15
SCHEMBL18911710 0.76 CYP2D6 (0.35) NR1I2ALDH1A1NR1H4TSHR
SCHEMBL18911705 0.74 MAPT (0.33) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL18911918 0.74 ADRB1 (0.46) ALDH1A1HPGDTSHR
SCHEMBL20681870 0.73 HCRTR1 (0.36) KCNH2ALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed